Joint Shape Representation and Classification for Detecting PDAC. (arXiv:1804.10684v1 [cs.CV])

We aim to detect pancreatic ductal adenocarcinoma (PDAC) in abdominal CT scans, which sheds light on early diagnosis of pancreatic cancer. This is a 3D volume classification task with little training data. We propose a two-stage framework, which first segments the pancreas into a binary mask, then compresses the mask into a shape vector and performs abnormality classification. Shape representation and classification are performed in a {\em joint} manner, both to exploit the knowledge that PDAC often changes the {\bf shape} of the pancreas and to prevent over-fitting. Experiments are performed on $300$ normal scans and $156$ PDAC cases. We achieve a specificity of $90.2\%$ (false alarm occurs on less than $1/10$ normal cases) at a sensitivity of $80.2\%$ (less than $1/5$ PDAC cases are not detected), which show promise for clinical applications.

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